August 26, 2026: the U.S. FDA approved daraxonrasib (RASONQUE) for metastatic pancreatic adenocarcinoma, the first RAS-targeted therapy approved for pancreatic cancer. All news →

First patient dosed in the Phase 3 RASolute 302 trial

RASolute 302, the first registrational Phase 3 trial of daraxonrasib, has begun in previously treated metastatic pancreatic ductal adenocarcinoma.

On October 21, 2024 Revolution Medicines announced that the first patient had been dosed in the Phase 3 RASolute 302 trial. The study compares daraxonrasib monotherapy with investigator's-choice standard chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma that has progressed after first-line therapy, and is the first registrational Phase 3 trial of daraxonrasib.

← Back to news Last updated: September 5, 2026
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